原著論文
長崎大学着任以降
30 Kubo R, Yoshikawa R, Fujii Y, Kawasaki T, Takazono T, Izumikawa K, Ariyoshi K, Mukae H, Yasuda J, Sustained humoral immunity in the patients recovered from severe fever with thrombocytopenia syndrome.Trop Med Health, 53(1):127, 2025
29 Nagai E, Ori D, Kano N, Ikegawa M, Kobiyama K, Ishii KJ, Kawasaki T, Kawai T, The Chitosan Nanoparticle-based Adjuvant CH-100 Orchestrates Multifaceted Innate Immune Activation via STING-Dependent and -Independent Pathways.Int Immunol., dxaf054, 2025
28 Ikegawa M, Kano N, Ori D, Fukuta M, Hirano M, Hewson R, Yoshii K, Kawai T, *Kawasaki T HuR (ELAVL1) regulates the CCHFV minigenome and HAZV replication by associating with viral genomic RNA. PLoS Negl Trop Dis. , 18(9):e0012553, 2024
2022年まで
27 *Kawasaki T, Ikegawa M, Yunoki K, Otani H, Ori D, Ishii KJ, Kuroda E, Takamura S, Kitabatake M, Ito T, Isotani A Kawai T, Alveolar macrophages instruct CD8+ T cell expansion by antigen cross-presentation in lung, Cell Rep., 41, 111828, 2022
26 Ong GH, Ori D, Kawasaki T, Kawai T, Inhibition of lipopolysaccharide-induced inflammatory responses by 1'-acetoxychavicol acetate Genes cells, Genes Cells, 27, 482-92, 2022
25 Lian BSX, *Kawasaki T, Kano N, Ori D, Ikegawa M, Isotani A, Kawai T, Regulation of Il6 expression by single CpG methylation in downstream of Il6 transcription initiation site, iScience, 25, 104118, 2022
24 Sok SPM, Ori D, Wada A, Okude H, Kawasaki T, Momota M, Nagoor NH, Kawai T, 1'-acetoxychavicol acetate inhibits NLRP3-dependent inflammasome activation via mitochondrial ROS suppression, Int Immunol., 33, 373-86, 2021
23 Momota M, Nagayama M, Okude H, Ishii KJ, Ori D, Kawasaki T, Kawai T, The Ca2+-dependent pathway contributes to changes in the subcellular localization and extracellular release of interleukin-33, Biochem Biophys Res Commun., 530, 699-705, 2020
22 Monwan W, *Kawasaki T, Hasan MZ, Ori D, Kawai T, Identification of nucleoporin 93 (Nup93) that mediates antiviral innate immune responses, Biochem Biophys Res Commun., 521, 1077-82, 2020
21 Zainol MIB, *Kawasaki T, Monwan W, Murase M, Sueyoshi T, Kawai T, Innate immune responses through Toll-like receptor 3 require human-antigen-R-mediated Atp6v0d2 stabilization, Sci Rep., 31, 20406, 2019
20 Putri D D P, *Kawasaki T, Murase M, Sueyoshi T, Deguchi M, Ori D, Suetsugu S Kawai T,PtdIns3P phosphatases MTMR3 and MTMR4 negatively regulate innate immune responses to DNA through modulating STING trafficking, J Biol Chem., 294, 8412-23, 2019 （co筆頭著者）
19 Sueyoshi T, Kawasaki T, Kitai Y, Ori D, Akira S, Kawai T, Hu antigen R regulates antiviral innate immune responses through the stabilization of mRNA for Polo-like kinase 2, J Immunol., 200, 3814-24, 2018
18 Murase M, *Kawasaki T, Hakozaki R, Sueyoshi T, Putri D D P, Kitai Y, Sato S, Ikawa M and Kawai T, Intravesicular acidification regulates lipopolysaccharide inflammation and tolerance through Toll-like receptor 4 trafficking, J Immunol., 200, 2798-808, 2018
17 *Kawasaki T, Ito K, Miyata H, Akira S and Kawai T, Deletion of PIKfyve alters alveolar macrophage populations and exacerbates allergic inflammation in mice, EMBO J., 37, 1707-18, 2017
16 Kitai Y, Kawasaki T, Sueyoshi T, Kobiyama K, Ishii KJ, Zou J, Akira S, Matsuda T, Kawai T,DNA-Containing Exosomes Derived from Cancer Cells Treated with Topotecan Activate a STING-Dependent Pathway and Reinforce Antitumor Immunity, J Immunol., 198, 1649-19, 2017
15 Maruyama K, Kawasaki T, Hamaguchi M, Hashimoto M, Furu M, Ito H, Fujii T, Takemura N, Karuppuchamy T, Kondo T, Kawasaki T, Fukasaka M, Misawa T, Saitoh T, Suzuki Y, Martino MM, Kumagai Y, Akira S, Bone-protective Functions of Netrin 1 Protein, J Biol Chem., 291, 23854-68, 2016
14 Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, Akira S, Kawai T, Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B, J Biol Chem. 290., 1269-80, 2015
13 Takemura N, Kawasaki T, Kunisawa J, Sato S, Lamichhane A, Kobiyama K, Aoshi T, Ito J, Mizuguchi K, Karuppuchamy T, Matsunaga K, Miyatake S, Mori N, Tsujimura T, Satoh T, Kumagai Y, Kawai T, Standley DM, Ishii KJ, Kiyono H, Akira S, Uematsu S, Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome, Nat Commun., 5, 3492, 2014
12 Maruyama K, Uematsu S, Kondo T, Takeuchi O, Martino MM, Kawasaki T, Akira S, Strawberry notch homologue 2 regulates osteoclast fusion by enhancing the expression of DC-STAMP, J Exp Med., 210, 1947-60, 2013
11 Kawasaki T, Takemura N, Standley DM, Akira S, Kawai T, The second messenger phosphatidylinositol-5-phosphate facilitates antiviral innate immune signaling, Cell Host Microbe., 14, 148-58, 2013
10 Maruyama K, Fukasaka M, Vandenbon A, Saitoh T, Kawasaki T, Kondo T, Yokoyama KK, Kidoya H, Takakura N, Standley D, Takeuchi O, Akira S, The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation, Immunity., 37, 1024-36, 2012
9 Unno M, Kawasaki T, Takahara H, Heizmann CW, Kizawa K, Refined crystal structures of human Ca(2+)/Zn(2+)-binding S100A3 protein characterized by two disulfide bridges, J Mol Biol., 408, 477-90, 2011
8 McCarl CA, Khalil S, Ma J, Oh-hora M, Yamashita M, Roether J, Kawasaki T, Jairaman A, Sasaki Y, Prakriya M, Feske S, Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection, J Immunol., 185, 5845-58, 2010
7 Kawasaki T, Ueyama T, Lange I, Feske S, Saito N, Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel,J Biol Chem. 285, 25720-30, 2010
6 McCarl CA, Picard C, Khalil S, Kawasaki T, Röther J, Papolos A, Kutok J, Hivroz C, Ledeist F, Plogmann K, Ehl S, Notheis G, Albert MH, Belohradsky BH, Kirschner J, Rao A, Fischer A, Feske S, ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia J Allergy Clin Immunol., 124, 1311-1318, 2009
5 Kawasaki T, Lange I, Feske S, A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels, Biochem Biophys Res Commun., 385, 49-54. 2009
4 Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N, Sequential binding of cytosolic Phox complex to phagosomes through regulated adaptor proteins: evaluation using the novel monomeric Kusabira-Green System and live imaging of phagocytosis, J Immunol., 181, 629-40, 2008
3 Adachi N, Kobayashi T, Takahashi H, Kawasaki T, Shirai Y, Ueyama T, Matsuda T, Seki T, Sakai N, Saito N, Enzymological analysis of mutant protein kinase Cgamma causing spinocerebellar ataxia type 14 and dysfunction in Ca2+ homeostasis, J Biol Chem. 283, 19854-63, 2008
2 Kawasaki T, Kobayashi T, Ueyama T, Shirai Y, Saito N, Regulation of clathrin-dependent endocytosis by diacylglycerol kinase delta: importance of kinase activity and binding to AP2alpha, Biochem J., 409, 471-9, 2008
1 Ueyama T, Tatsuno T, Kawasaki T, Tsujibe S, Shirai Y, Sumimoto H, Leto TL, Saito N, A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox, Mol Biol Cell., 18, 441-54. 2007
総説
長崎大学着任以降
8 *Kawasaki T, Ikegawa M, Kawai T, Antigen-presenting cells and lung CD8⁺ resident memory T cells coordinate local immune protection and shape responses to respiratory virus infection International Immunology, dxaf033, 2023
7 川﨑拓実, 河合太郎, 肺胞マクロファージの細胞性免疫活性化における役割, 臨床免疫・アレルギー科 80(4) 509-515 2023
2022年まで
6 *Kawasaki T, Ikegawa M, Kawai T, Antigen presentation in lung, Front Immunol., 10.3389/fimmu.2022.860915, 2022
5 Ong GH, Lian BSX, Kawasaki T and Kawai T, Exploration of Pattern Recognition Receptor Agonists as Candidate Adjuvants, Front Cell Infect Microbiol., 11, 745016, 2021
4 *Kawasaki T, Kawai T, Discrimination Between Self and Non-Self-Nucleic Acids by the Innate Immune System., Int Rec Cell Mol Biol., 344, 1-30, 2019
3 奥出遥奈、中川実優、川﨑拓実、河合太郎, 炎症・自然免疫研究の進歩と血液疾患, 血液内科, 5, 551, 2017
2 Kawasaki T, Kawai T, Toll-like receptor signaling pathway,Front Immunol., 5, 461, 2014
1 Kawasaki T, Kawai T, Akira S, Recognition of nucleic acids by pattern-recognition receptors and its relevance in autoimmunity, Immunol Rev. 243, 61-73, 2011