PUBLICATION
        
      
      
        
        
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            Kobayashi S, Fukuda Y, Yoshii K, Thammahakin P, Maezono K, Eyer L,
            Ruzek D, Kariwa H (2023) Development of recombinant West Nile virus
            expressing mCherry reporter protein. J Virol Methods 317:114744
          
 
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            Kobayashi S, Kawakami R, Takeda C, Maezono K, Thammahakin P, Eguchi
            H, Hang'ombe BM, Orba Y, Sawa H, Yoshii K, Kariwa H (2023) Ubiquitin
            accumulation induced by the finger and palm sub-domains of NS5
            modulates the replication of West Nile virus. Virology 588:109902
          
 
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            Ohira M, Yoshii K, Aso Y, Nakajima H, Yamashita T, Takahashi-Iwata
            I, Maeda N, Shindo K, Suenaga T, Matsuura T, Sugie K, Hamano T, Arai
            A, Furutani R, Suzuki Y, Kaneko C, Kobayashi Y, Campos-Alberto E,
            Harper LR, Edwards J, Bender C, Pilz A, Ito S, Angulo FJ, Erber W,
            Madhava H, Moisi J, Jodar L, Mizusawa H, Takao M (2023) First
            evidence of tick-borne encephalitis (TBE) outside of Hokkaido Island
            in Japan. Emerg Microbes Infect 12:2278898
          
 
        
       
      
        
        
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            Ozeki T, Abe H, Ushijima Y, Nze-Nkogue C, Akomo-Okoue EF, Ella GWE,
            Koumba LBM, Nso B, Mintsa-Nguema R, Makouloutou-Nzassi P, Makanga
            BK, Nguelet FLM, Ondo GN, Mbadinga M, Igasaki Y, Okada S, Hirano M,
            Yoshii K, Lell B, Bonney LC, Hewson R, Kurosaki Y, Yasuda J (2022)
            Identification of novel orthonairoviruses from rodents and shrews in
            Gabon, Central Africa. J Gen Virol 103  10.1099/jgv.0.001796
          
 
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            Tamiya K, Kobayashi S, Yoshii K, Kariwa H (2022) Analysis of the
            relationship between replication of the Hokkaido genotype of Puumala
            orthohantavirus and autophagy. Virus Res 318:198830 
            10.1016/j.virusres.2022.198830
          
 
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            Tsujino D, Yoshii K, Kajiyama M, Takahashi Y, Maekawa N, Kariwa H,
            Kobayashi S (2022) Necroptosis of neuronal cells is related to the
            neuropathology of tick-borne encephalitis. Virus Res 321:198914 
            10.1016/j.virusres.2022.198914
          
 
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            Hirano M, Sakurai Y, Urata S, Kurosaki Y, Yasuda J, Yoshii K (2022)
            A screen of FDA-approved drugs with minigenome identified
            tigecycline as an antiviral targeting nucleoprotein of Crimean-Congo
            hemorrhagic fever virus. Antiviral research 200:105276 doi:
            10.1016/j.antiviral.2022.105276.
          
 
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            Nishiyama S, Hirano M, Muto M, Kambara M, Ito N, Kobayashi S, Kariwa
            H, Yoshii K (2022) Y-shaped RNA Secondary Structure of a Noncoding
            Region in the Genomic RNA of Tick-Borne Encephalitis Virus Affects
            Pathogenicity. Microbiol Immunol 66: 234-237 doi:
            10.1111/1348-0421.12971.
          
 
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            Takahashi Y, Kobayashi S, Nakao R, Kariwa H, Yoshii K (2022)
            Characterization of tick-borne encephalitis virus isolated from tick
            infesting dog in central Hokkaido in 2018. Ticks and tick-borne
            diseases 13:101900 doi: 10.1016/j.ttbdis.2022.101900.
          
 
        
       
      
        
        
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            Maezono K, Kobayashi S, Tabata K, Yoshii K, Kariwa H (2021)
            Development of a highly specific serodiagnostic ELISA for West Nile
            virus infection using subviral particles. Sci Rep 11:9213
          
 
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            Sasaki K, Honma M, Nakao M, Sasaki M, Hashimoto Y, Ishida-Yamamoto
            A, Yoshii K (2021) Survey to detect tick-borne encephalitis virus
            from human-feeding ticks in Hokkaido, Japan. J Dermatol
            Jul;48(7):1094-1097. doi: 10.1111/1346-8138.15865.
          
 
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            Harima H, Orba Y, Torii S, Qiu Y, Kajihara M, Eto Y, Matsuta N,
            Hang'ombe BM, Eshita Y, Uemura K, Matsuno K, Sasaki M, Yoshii K,
            Nakao R, Hall WW, Takada A, Abe T, Wolfinger MT, Simuunza M, Sawa H
            (2021) An African tick flavivirus forming an independent clade
            exhibits unique exoribonuclease-resistant RNA structures in the
            genomic 3'-untranslated region. Sci Rep 11:4883 doi:
            10.1038/s41598-021-84365-9
          
 
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            Talactac MR, Hernandez EP, Hatta T, Yoshii K, Kusakisako K, Tsuji N,
            Tanaka T (2021) The antiviral immunity of ticks against transmitted
            viral pathogens. Developmental and comparative
            immunology 119:104012  doi: 10.1016/j.dci.2021.104012
          
 
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            Haviernik J, Eyer L, Yoshii K, Kobayashi S, Cerny J, Nougairede A,
            Driouich JS, Volf J, Palus M, de Lamballerie X, Gould EA, Ruzek D
            (2021) Development and characterization of recombinant tick-borne
            encephalitis virus expressing mCherry reporter protein: a new tool
            for high-throughput screening of antiviral compounds, and
            neutralizing antibody assays. Antiviral research 185:104968 doi:
            10.1016/j.antiviral.2020.104968.
          
 
        
       
      
        
        
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            Hernandez EP, Talactac MR, Santos Vitor RJ, Yoshii K, Tanaka T
            (2020) An Ixodes scapularis glutathione S-transferase plays a role
            in cell survival and viability during Langat virus infection of a
            tick cell line. Acta Trop 214:105763  doi:
            10.1016/j.actatropica.2020.105763.
          
 
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            Yoshii K, Takahashi-Iwata I, Shirai S, Kobayashi S, Yabe I, Sasaki H
            (2020) A Retrospective Epidemiological Study of Tick-Borne
            Encephalitis Virus in Patients with Neurological Disorders in
            Hokkaido, Japan. Microorganisms 8:1672 doi:
            10.3390/microorganisms8111672. 【プレスリリースはこちら(https://www.nagasaki-u.ac.jp/ja/guidance/kouhou/press/file/20201127_2.pdf)
          
 
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            Kobayashi S, Kaneko C, Kawakami R, Hasebe R, Sawa H, Yoshii K,
            Kariwa H (2020) Amino acid 159 of the envelope protein affects viral
            replication and T-cell infiltration by West Nile virus in
            intracranial infection. Sci Rep 10:7168  doi:
            10.1038/s41598-020-64199-7.
          
 
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            Ikebuchi R, Isaac AW, Yoshii K, Doulabi EM, Lof L, Azimi A, Chen L,
            Fredolini C, Gallini R, Landegren U, Kamali-Moghaddam M (2020) Human
            proteins incorporated into tick-borne encephalitis virus revealed by
            in situ proximity ligation. Biochem Biophys Res Commun 525:714-719
            doi: 10.1016/j.bbrc.2020.02.143.
          
 
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            Kusakisako K, Morokuma H, Talactac MR, Hernandez EP, Yoshii K,
            Tanaka T (2020) A Peroxiredoxin From the Haemaphysalis longicornis
            Tick Affects Langat Virus Replication in a Hamster Cell Line. Front
            Cell Infect Microbiol 10:7 doi: 10.3389/fcimb.2020.00007.
          
 
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            Takahashi Y, Kobayashi S, Ishizuka M, Hirano M, Muto M, Nishiyama S,
            Kariwa K, Yoshii K Characterization of Tick-borne Encephalitis Virus
            Isolated From a Tick in Central Hokkaido in 2017 J Gen Virol
            101:497-509 doi: 10.1099/jgv.0.001400
          
 
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            Kobayashi S, Yoshii K, Phongphaew W, Muto M, Hirano M, Orba Y, Sawa
            H, Kariwa H (2020) West Nile virus capsid protein inhibits autophagy
            by AMP-activated protein kinase degradation in neurological disease
            development. PLoS Pathog 16:e1008238 【プレスリリースはこちら(https://www.hokudai.ac.jp/news/2020/01/post-618.html)
          
 
        
       
      
        
        
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            Wastika CE, Sasaki M, Yoshii K, Anindita PD, Hang'ombe BM, Mweene
            AS, Kobayashi S, Kariwa H, Carr MJ, Hall WW, Eshita Y, Orba Y, Sawa
            H (2019) Serological evidence of Zika virus infection in non-human
            primates in Zambia. Arch Virol 164:2165-2170
          
 
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            Shimoda H, Hayasaka D, Yoshii K, Yokoyama M, Suzuki K, Kodera Y,
            Takeda T, Mizuno J, Noguchi K, Yonemitsu K, Minami S, Kuwata R,
            Takano A, Maeda K (2019) Detection of a novel tick-borne flavivirus
            and its serological surveillance. Ticks and tick-borne diseases
            10:742-748
          
 
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            Zhang Q, Li N, Deng C, Zhang Z, Li X, Yoshii K, Ye H, Zhang B (2019)
            Trans Complementation of Replication-defective Omsk Hemorrhagic
            Fever Virus for Antiviral Study. Virol Sin 34:412-422
          
 
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            Yoshii K (2019) Epidemiology and pathological mechanisms of
            tick-borne encephalitis. J Vet Med Sci 81:343-347
          
 
        
       
      
        
        
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            Matsuda M, Yamanaka A, Yato K, Yoshii K, Watashi K, Aizaki H,
            Konishi E, Takasaki T, Kato T, Muramatsu M, Wakita T, Suzuki R
            (2018) High-throughput neutralization assay for multiple
            flaviviruses based on single-round infectious particles using dengue
            virus type 1 reporter replicon. Sci Rep 8:16624
          
 
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            Hernandez EP, Kusakisako K, Talactac MR, Galay RL, Yoshii K, Tanaka
            T (2018) Induction of intracellular ferritin expression in
            embryo-derived Ixodes scapularis cell line (ISE6). Sci Rep 8:16566
          
 
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            Nakayasu M, Hirano M, Muto M, Kobayashi S, Kariwa H, Yoshii K (2018)
            Development of a serodiagnostic IgM-ELISA for tick-borne
            encephalitis virus using subviral particles with strep-tag. Ticks
            and tick-borne diseases 9:1391-1394 doi: 10.1038/s41598-018-34865-y
          
 
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            Matsuno K, Kajihara M, Nakao R, Nao N, Mori-Kajihara A, Muramatsu M,
            Qiu Y, Torii S, Igarashi M, Kasajima N, Mizuma K, Yoshii K, Sawa H,
            Sugimoto C, Takada A, Ebihara H (2018) The Unique Phylogenetic
            Position of a Novel Tick-Borne Phlebovirus Ensures an Ixodid Origin
            of the Genus Phlebovirus. mSphere 3 pii: e00239-18
          
 
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            Talactac MR, Yoshii K, Hernandez EP, Kusakisako K, Galay RL,
            Fujisaki K, Mochizuki M, Tanaka T (2018) Vector competence of
            Haemaphysalis longicornis ticks for a Japanese isolate of the
            Thogoto virus. Sci Rep 8:9300
          
 
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            Yoshii K, Sato K, Ishizuka M, Kobayashi S, Kariwa H, Kawabata H
            (2018) Serologic Evidence of Tick-Borne Encephalitis Virus Infection
            in a Patient with Suspected Lyme Disease in Japan. Am J Trop Med Hyg
            99:180-181
          
 
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            Kusakisako K, Hernandez EP, Talactac MR, Yoshii K, Umemiya-Shirafuji
            R, Fujisaki K, Tanaka T (2018) Peroxiredoxins are important for the
            regulation of hydrogen peroxide concentrations in ticks and tick
            cell line. Ticks and tick-borne diseases 9: 870-881
          
 
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            山口宏樹、駒込理佳、三好正浩、石田勢津子、長野秀樹、岡野素彦、島田光平、冨加見昌孝、田中研伸、竹内德男、好井健太朗、小林進太郎、苅和宏明(2018)「2017年の北海道におけるダニ媒介脳炎」病原微生物検出情報
            39: 46-47
          
 
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            Muto M, Kamitani W, Sakai M, Hirano M, Kobayashi S, Kariwa H, Yoshii
            K (2018) Identification and Analysis of Host Proteins that Interact
            with the 3'-Untranslated Region of Tick-Borne Encephalitis Virus
            Genomic RNA. Virus Res. 249: 52-56
          
 
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            Fuzik T, Formanova P, Ruzek D, Yoshii K, Niedrig M, Plevka P (2018)
            Structure of tick-borne encephalitis virus and its neutralization by
            a monoclonal antibody. Nat Commun 9:436
          
 
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            Lundu T, Tsuda Y, Ito R, Shimizu K, Kobayashi S, Yoshii K,
            Yoshimatsu K, Arikawa J, Kariwa H (2018) Targeting of severe fever
            with thrombocytopenia syndrome virus structural proteins to the
            ERGIC (endoplasmic reticulum Golgi intermediate compartment) and
            Golgi complex. Biomed Res. 39:27-38.
          
 
        
       
      
        
        
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            Hirano M, Muto M, Sakai M, Kondo H, Kobayashi S, Kariwa H, Yoshii K
            (2017) Dendritic transport of tick-borne flavivirus RNA by neuronal
            granule affects development of the neurological disease. Proc Natl
            Acad Sci U S A. 114:9960-9965 doi: 10.1073/pnas.
            【プレスリリースはこちら (https://www.vetmed.hokudai.ac.jp/news/topics/press_release_170904/):北海道新聞掲載】
          
 
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            Eyer L, Kondo H, Zouharová D, Hirano M, Valdés J, Muto M, Kastl T,
            Kobayashi S, Haviernik J, Igarashi M, Kariwa H, Vaculovicova M,
            Cerny J, Kizek R, Kröger A, Lienenklaus S, Dejmek M, Nencka R, Palus
            M, Salat J, Clercq ED, Yoshii K, Růžek D (2017) Escape of tick-borne
            flavivirus from 2’-C-methylated nucleoside antivirals is mediated by
            a single conservative mutation in NS5 that has a dramatic effect on
            viral fitness. J Virol. doi: 10.1128/JVI.01028-17. doi:
            10.1128/JVI.01028-17.
          
 
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            Yoshii K, Kojima R, Nishiura H (2017) Unrecognized subclinical
            infections with tick-borne encephalitis virus in Japan. Emerg Infect
            Dis. 23:1753-1754  doi: 10.3201/eid2310.170918.
          
 
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            Talactac MR, Yoshii K, Hernandez EP, Kusakisako K, Galay RL,
            Fujisaki K, Mochizuki M, Tanaka T (2017) Synchronous Langat Virus
            Infection of Haemaphysalis longicornis Using Anal Pore
            Microinjection. Viruses 9(7). doi: 10.3390/v9070189.
          
 
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            Fukuhara T, Tamura T, Ono C, Shiokawa M, Mori H, Uemura K, Yamamoto
            S, Kurihara T, Okamoto T, Suzuki R, Yoshii K, Kurosu T, Igarashi M,
            Aoki H, Sakoda Y, Matsuura Y (2017) Host-derived apolipoproteins
            play comparable roles with viral secretory proteins Erns and NS1 in
            the infectious particle formation of Flaviviridae. PLoS Pathog
            13:e1006475 doi: 10.1371/journal.ppat.1006475.
          
 
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            Talactac MR, Yada Y, Yoshii K, Hernandez EP, Kusakisako K, Maeda H,
            Galay RL, Fujisaki K, Mochizuki M, Tanaka T (2017) Characterization
            and antiviral activity of a newly identified defensin-like peptide,
            HEdefensin, in the hard tick Haemaphysalis longicornis. Dev Comp
            Immunol. 68:98-107
          
 
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            Kobayashi S, Yoshii K, Hirano M, Muto M, Kariwa H. (2017) A Novel
            Reverse Genetics System for Production of Infectious West Nile Virus
            using Homologous Recombination in Mammalian Cells. J Virol Methods.
            240:14-20
          
 
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            Nakao R, Matsuno K, Qiu Y, Maruyama J, Eguchi N, Nao N, Kajihara M,
            Yoshii K, Sawa H, Takada A, Sugimoto C (2017) Putative RNA viral
            sequences detected in an Ixodes scapularis-derived cell line. Ticks
            Tick Borne Dis. 8:103-111
          
 
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            好井健太朗、田島康敬、坂東敬介、守内玲寧「2016年に北海道で発生したダニ媒介性脳炎症例」病原微生物検出情報
            38:126
          
 
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            Yoshii K., Song JY, Park SB, Yang J, Schmitt HJ (2017) Tick-borne
            encephalitis in Japan, the Republic of Korea, and China. Emerg
            Microbes Infect. 6:e82 doi: 10.1038/emi.2017.69